Ubiquitin specific protease 7 (USP7) is one of the deubiquitinating enzymes (DUB) that erases ubiquitin and protects substrate protein from degradation.Full activity of USP7 requires the C-terminal Ub-like domains fold back onto the catalytic domain, allowing the remodeling of the active site to a catalytically competent state by the C-terminal Dow
Analysis of Root Causes for Chemical Accidents Basis on Business Process Model for Plant Maintenance
Unintended release of material from chemical plants becomes a serious problem that may lead to a fire, explosion or human health incident.Plant maintenance is concerned, the direct cause of the unintended release can be clarified, e.g.strength decline by chemical and/or physical deterioration, imperfectness of isolation at overhaul operation, and B
Effects of gear modifications in a North Atlantic pelagic longline fishery: A multiyear study.
The threat of population declines caused by pelagic longline fisheries in Bubbler the Atlantic has increased the concern to find strategies that minimize the bycatch and mortality of non-target marine animals.Gear modification, such as the use of circle hooks instead of conventional J-hooks, has been identified as an effective bycatch reduction str
The Double-Edged Sword: Unraveling the Dual Outcomes of Workplace Humor on the Social Identity of Employees
Building on the social identity theory, this conceptual article proposes a process model to understand the linkage between workplace humor and the social identity change experiences of employees.Further, it identifies the underlying mechanisms and conditions which impact the positive and negative identity changes during this process.Based on the pr
Biodistribution and Biosafety of a Poly(Phosphorhydrazone) Dendrimer, an Anti-Inflammatory Drug-Candidate
Dendrimers are nanosized, arborescent polymers of which size and structure are perfectly controlled.This is Triathlon - Accessoires one reason why they are widely used for biomedical purposes.Previously, we showed that a phosphorus-based dendrimer capped with anionic azabisphosphonate groups (so-called ABP dendrimer) has immuno-modulatory and anti-